Research

Project Name: Hope-Home – Health Outcomes of People Experiencing Homeless in Older Middle Age Study
Funded by National Institute of Aging
Principle Investigator: Dr. Margot Kushel
Duration: 9/30/2012 – 05/31/2017

The goal of the Hope-Home study is to determine the prevalence, severity, trajectory and consequences of geriatric conditions in homeless adults age 50 and older in order to guide prevention, health care, social service and housing interventions. The average age of homeless adults in the U.S. has risen dramatically: almost half of the homeless population is 50 years and older, a significant increase from 20 years ago. Little is known about the role that aging-related conditions play in causing poor outcomes in this population, including the characteristics and consequences of geriatric conditions that may be a substantial factor in prolonging homelessness. These data from the Hope-Home study are needed for evidence-based design and effective implementation of policies and programs that do not currently address aging issues.
Links: National Institute of Aging

Project Name: Enhancing Mexican Capacity for CVD Policy Research Funded by NIH, Fogarty International Center
Multiple Principal Investigators: Dr. Bibbins-Domingo and Dr. Alicia Fernandez
Duration: 12/1/12 – 11/30/15

This project brings together teams from the University of California, San Francisco and from the Instituto Nacional de Salud Publica, Cuernavaca, to build a CHD Policy Model-Mexico and to create capacity within Mexico to use the Model to conduct Mexico and global comparative policy oriented research.

Project Name: Discovery and Healthcare Innovation to Address Disparities in Stroke (DIADS)
Funded by NIH NINDS U54
Multiple Principal Investigators: Dr. Bibbins-Domingo and Dr. Stephen Sidney
Duration: 10/1/12 – 9/30/17

Northern California (KPNC) and University of California, San Francisco (UCSF) Collaborative Center.” To create a regional collaborative center to study the causes of disparities in stroke and design and test interventions aimed at addressing these disparities.

Project Name: Outcomes Modeling for VA Return on Investment Analysis
Funded by Department of Veterans Affairs – VA Puget Sound Healthcare System – Seattle Division
Principal Investigator: Dr. Bibbins-Domingo
Duration: 9/24/12-09/23/13

To develop a VA-tailored Coronary Heart Disease (CHD) Policy Model to predict changes in health outcomes, utilization and costs for Veterans with chronic heart disease.

Project Name: Addressing Disparities in Chronic Disease with a Teen and Young Adult Focus
Funded by NIMHD, Comprehensive Centers of Excellence
Principal Investigator: Dr. Bibbins-Domingo
Duration: 8/27/12-2/28/17

To create the Center for Health And Risk in Minority youth and adults (CHARM), a new comprehensive center of excellence that will focus on chronic conditions and chronic disease risk in Latinos, African Americans and Asians across the arc from adolescence to young adulthood (age 8 to 35 years) as targeted prevention at this age group has the potential to greatly impact minority health and health disparities.

Project Name: Comparative Effectiveness of Policies to Reduce Dietary Salt Intake in the Pacific Rim
Funded by University of California – Pacific Rim Research Program
Principal Investigator: Dr. Bibbins-Domingo
Duration: 7/1/12-6/30/13

To adapt the Cardiovascular Disease (CVD) Policy Model, a validated computer simulation of CHD in the US adult population over age 35 years to Argentina, Chile, and China, using their respective data on CHD risk factors to create a country specific CVD Policy Model and evaluate the anticipated effectiveness and cost-effectiveness of the country-specific sodium reduction interventions.

Project Name: Modeling Optimal Strategies to Prevent Cardiovascular Events in Older Adults
Funded by NIH/NIA
Principal Investigator: Dr. Odden, Dr. Bibbins-Domingo is a Mentor on the project
Duration: 2/1/12-1/31/13

To develop a comprehensive evidence base for prevention of cardiovascular events in adults aged 75 years and older. We will identify the strongest novel and traditional risk factors for cardiovascular disease in the Cardiovascular Health Study, an ongoing NIH-funded cohort study of elderly adults. Next, we will use the results of these analyses to inform computer simulations of cardiovascular morbidity and mortality in older adults, in order to identify the most promising targets for cardiovascular disease prevention at the lowest risk for unintended side effects.

Project Name: Clinical and Translational Sciences Institute Funded by NIH
Principal Investigator: Dr. Johnston; Co-Investigator: Dr. Bibbins-Domingo
Duration 7/1/11 – 6/30/16

To forge a uniquely transformative, novel, and integrative academic home for Clinical and Translational Science that has the consolidated resources to:1) captivate, advance, and nurture a cadre of well-trained multi- and inter-disciplinary investigators and research teams; 2) create an incubator for innovative research tools and information technologies; and 3) synergize multi-disciplinary and interdisciplinary clinical and translational research and researchers to catalyze the application of new knowledge and techniques to clinical practice at the front lines of patient care. Dr. Bibbins-Domingo is the Director of the CTSI K Scholars Program, a career development program for junior faculty at UCSF engaged in clinical and translational research.
Links: CTSI – K Scholars Program

Project Name: Enhancing Mexican Capacity for CVD Policy Research Funded by UC Institute for Mexico and the United States
Principal Investigator: Dr. Bibbins-Domingo
Duration: 7/1/11 – 12/31/13

To develop a Mexican version of the Coronary Heart Disease (CHD) Policy Model (“CHD Policy Model-Mexico”) and create both a useful tool for the evaluation of clinical and public health interventions in Mexico.
Links: UCMEXUS

Project Name: The Impact and Cost-Effectiveness of Blood Pressure and Lipid Control in Older Elders
Funded by American Heart Association
Principal Investigator: Dr. Odden; Co-Investigator: Dr. Bibbins-Domingo
Duration: 7/1/11 – 6/3/13

To evaluate the population impact and cost-effectiveness of guidelines for blood pressure and lipid control in older elders. We will account for the attenuated effectiveness of antihypertensive medications and statins in older adults, as well as the increased risk of side effects and polypharmacy. This project will help inform the development of future guidelines that account for the unique needs of elderly adults.

Project Name: Comparative Effectiveness Analysis of Treat-to-Target and Risk Based Blood Pressure Control Policy
Funded by NIH/NHLBI
Principal Investigator: Dr. Moran; Co-Investigator: Dr. Bibbins-Domingo
Duration: 8/19/11 – 6/30/14

To assess the effectiveness of United States national blood pressure control policy (Joint National Committee guidelines), compare current guidelines to alternative risk- or age-based approaches, and estimate guideline effectiveness in the face of future demographic shifts in the U.S.

Project Name: Establishing a Surveillance System for Chronic Kidney Disease in the US
Funded by CDC/ONDIEH/HCCDPHP
Principal Investigator: Dr. Powe; Co-Investigator: Dr. Bibbins-Domingo
Duration: 9/30/11-9/29/16

Project to design and create a surveillance system for chronic kidney diseases in the United States.

Project Name: Addressing Disparities in Chronic Disease with a Teen and Young Adult Focus
Funded by NIMHD Comprehensive Centers of Excellence
Principal Investigator: Dr. Bibbins-Domingo; Co-Investigator: Dr. Dean Schillinger
Duration: 8/27/12 – 2/28/17

To create the Center for Health And Risk in Minority youth and adults (CHARM), a new comprehensive center of excellence that will focus on chronic conditions and chronic disease risk in Latinos, African Americans and Asians across the arc from adolescence to young adulthood (age 8 to 35 years) as targeted prevention at this age group has the potential to greatly impact minority health and health disparities. Role: Co-Investigator; Outreach Core Director.

Project Name: Primary Care Intervention Promoting Hearing Health Care Service-Access and Use
Funded by NIH NIDCH
Principal Investigator: Dr. Wallhagen; Co-Investigator: Dr. Dean Schillinger
Duration: 3/1/13 – 2/29/16

The purpose of the R21 phase is to develop, pilot test, and further refine a screening and educational program for older adults with hearing loss that is designed to promote access to and effective use of hearing health services (HHC). The purpose of the R33 phase of the proposal is to utilize a randomized controlled trial to test the comparative effectiveness within a primary care setting of three protocols for older adults ≥ 60 years of age who are not currently wearing hearing aids and who screen positive as at risk for hearing loss on subsequent access to and effective use of hearing health services. Role: Co-investigator.

Project Name: Feasibility of Implementation of International Standards of TB Care Guidelines in Uganda
Funded by NIH/NIAD
Principal Investigator: Dr. Cattamanchi; Co-Investigator: Dr. Handley
Duration: 7/1/11 – 6/30/2013

The study is a pilot intervention components to determine the feasibility and impact on objective measures of International Standards of TB Care (ISTC) adherence.

Project Name: CTSI-Community Engagement and Health Policy Program: Clinical and Translationa lScience Institute
Funded by NIH/NCRR
Principal Investigator: Dr. Johnston; Co-Investigator: Dr. Handley
Duration: 9/30/06 – 6/30/2016

The purpose of this grant is to forge a transformative, novel, and integrative academic home for Clinical and Translational Science to:1) captivate, advance, and nurture a cadre of well-trained inter-disciplinary investigators and research teams; 2) create an incubator for innovative research tools and information technologies; and 3) synergize multi-disciplinary and inter-disciplinary clinical and translational research and researchers to catalyze the application of new knowledge and techniques to clinical practice at the front lines of patient care. Dr. Handley is one of the CTSI-Community Engagement faculty leading the UCSF component of the SF Bay Health Improvement Project focused on Obesity Prevention and Healthy Eating. She also co-directs the Implementation and Dissemination Sciences Training Program. Co-Investigator- CTSI-Community Engagement and Health Policy Program Co-Director, Training Program in Implementation and Dissemination Sciences (IDS)
Links: TSI – Community Engagement & Health Policy

Project Name: CA4Health Evaluation Plan: Community Transformation Grants in Twelve California Counties
Funded by Centers for Disease Control
Principal Investigator: Ritchie; Co-Investigator: Dr. Hilary Seligman
Duration: 2012-2016

The goals of the CA4 Health evaluation are to: 1) highlight the accomplishments of CA4Health grantees, 2) gain knowledge related to the impact of their intervention efforts, 3) learn from the challenges grantees confront in working to make county improvements, and 4) document feasible population outcomes resulting from the interventions.